Glicaramide

 Glicaramide (SQ-65993) is an orally bioavailable anti-diabetic medication.[1] It has a similar potency as glibenclamide (glyburide) in the class of medication known as sulfonylureas. Its structure is similar since it has a cyclic acyl group which replaces the latter's 2-methoxy-5-chlorobenzyl.[2] Same as glibenclamide, it is classified as a second-generation sulfonylurea. It may have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide.[2]

Glicaramide
Glicaramide.svg
Clinical data
ATC code
  • None
Identifiers
IUPAC name
  • N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-1-ethyl-3-methyl-4-(3-methylbutoxy)pyrazolo[3,4-b]pyridine-5-carboxamide
CAS Number
  • 36980-34-4
PubChem CID
  • 65799
ChemSpider
  • 59215
UNII
  • UK5SR22C8Q
ChEMBL
  • ChEMBL2106430
CompTox Dashboard (EPA)
  • DTXSID60190471 Edit this at Wikidata
Chemical and physical data
FormulaC30H42N6O5S
Molar mass598.76 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • C0CCCCC0NC(=O)NS(=O)(=O)c1ccc(cc1)CCNC(=O)c2cnc3n(CC)nc(C)c3c2OCCC(C)C

This article uses material from the Wikipedia article
 Metasyntactic variable, which is released under the 
Creative Commons
Attribution-ShareAlike 3.0 Unported License
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